Private Penny: The Resistance is part of the requirements for the undergraduate thesis of a fine arts major and two game development majors studying at Ateneo de Mania University. The game is still a work in progress.

The main inspiration for the Private Penny: The Resistance is antibiotic resistance. Bacteria are increasingly being resistant to currently known antibiotics, which poses a threat to the health of the populace. One of the major factors for this occurrence is the misuse and abuse of antibiotics, which can easily be avoided by educating consumers about their medical choices and their consequences. Antibiotic resistance poses a serious threat to the health of humans because as more and more bacteria grow resistant to currently existing antibiotics, more and more people are at risk for bacterial infections, some of which can be lethal.

The creators of the game hope to inform the public about antibiotic resistance and what can be done to avoid furthering this phenomena.