Khatm-e-Nubuwwat means that Hazrat Muhammad (ﷺ) is the Last of the Prophets. The process and routine of appointing Prophets and Messengers by Almighty Allah has been terminated, finished, ended, stopped, and sealed. None will be appointed as Prophet after Hazrat Muhammad (ﷺ). His Prophet hood will continue until the dooms day and even afterwards.
There are many Quranic verses that confirm this concept, in this Android Application, you will know all of that and understand and will knowledge about that.