The ACMI was founded in 1958 by a small group of eminent internists from Bogotá at the initiative of doctors Rafael Carrizosa Argáez and Roberto De Zubiría Consuegra, who were elected as its first President and Secretary, respectively. It was then statutorily defined as "an entity of a scientific and union nature, whose function should be the grouping of doctors who practice Internal Medicine" in Colombia.