Being naturally nocturnal, voracious nibblers, and rapid reproducers (starting at the tender age of 6 weeks) how does one go about dealing with mice without turning to mainstream methods? Enter a fun little idea called integrated pest management It takes some more work, dedication, and thought than other methods, but you can manage without using toxic chemicals, which makes it far superior in my opinion. IPM involves pest proofing your home by sealing up any potential entrances, keeping food well sealed and securely locked away, knowing your pests habits, likes/dislikes, and eliminating any water sources.