A delight for readers of Where'd You Go, Bernadette, this blockbuster debut set in 1960s California features the singular voice of Elizabeth Zott, a scientist whose career takes a detour when she becomes the star of a beloved TV cooking show.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it's the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans, the lonely, brilliant, Nobel Prize–nominated grudge holder who falls in love with—of all things—her mind. True chemistry results.

Like science, though, life is unpredictable. Which is why a few years later Eizabeth Zott finds herself not only a single mother but also the reluctant star of America's most beloved cooking show, Supper at Six. Elizabeth's unusual...