🌟 Bioinorganic Chemistry Notes

Bioinorganic Chemistry (2025–2026 Edition) is a uni-level, updated, research-oriented textbook for students of Bioinorganic Chem, Biology, Chem, Biochem, Med Chem & Life Sci. It covers metals in bio systems, metalloproteins, enzyme mech, redox proc, metal complexes, medicinal apps, toxicology, biomineralization & adv bioinorg research. Combines classical principles with modern tech, ideal for learning, research prep & clarity.

Full syllabus with unit-wise chapters, topic-wise coverage, MCQs, quizzes for exams, lab research & higher study. Helps students, educators & researchers strengthen understanding of metal ions, electron transfer, enzyme catalysis, oxygen transport, analytical tech, biomineralization & emerging bioinorg directions.

🌟 Unit 1: Intro to Bioinorg Chem
• Def, scope & importance
• Historical dev
• Bio roles of inorg elements
• Classification: essential, beneficial, toxic
• Metallomics & metal-ligand interact
• Inorg cofactors & prosthetic groups
• Apps in med & industry

🌟 Unit 2: Essential Metal Ions
• Alkali Na+, K+
• Alkaline Mg2+, Ca2+
• Fe role in life
• Zn enzymatic func
• Cu & Mn redox proc
• Co & vit B12
• Mo & V enzymes
• Trace & ultra-trace
• Deficiency & toxicity

🌟 Unit 3: Techniques
• UV-Vis metalloprotein
• EPR paramag centers
• Mössbauer Fe proteins
• X-ray crystallography
• NMR metallobiomolecules
• Electrochem for redox
• Magnetic susceptibility
• Isotopic labeling & tracers
• Comput & theoretical bioinorg

🌟 Unit 4: Metal Transport & Storage
• Bio transport & ion channels: Na+, K+, Ca2+
• Active transport: Na+-K+ ATPase
• Metal homeostasis & cell balance
• Metallochaperones
• Storage: ferritin & transferrin
• Metallothioneins & detox
• Ion transport disorders
• Artificial & biomimetic transport

🌟 Unit 5: O2 Transport & Storage
• Hemoglobin & Myoglobin
• Cooperative binding & allosteric
• Bohr effect & physiological signif
• Hemocyanin & hemerythrin
• Synthetic O2 carriers
• O2 affinity & regulation
• Disorders (e.g., sickle cell)
• Comparative O2-binding

🌟 Unit 6: Electron Transfer & Redox
• Bio electron transfer & Marcus theory
• Fe-S clusters & cytochromes
• Blue Cu proteins & non-heme Fe
• Multi-electron redox & long-range ET
• Artificial ET models

🌟 Unit 7: Metalloenzymes & Catalysis
• Gen features
• Zn: carbonic anhydrase, carboxypeptidase
• Fe: catalase, peroxidase, cytochrome P450
• Cu: SOD, tyrosinase
• Ni: urease, hydrogenase
• Mo: nitrogenase, xanthine oxidase
• V: haloperoxidases
• Catalysis mech & biomimetic models

🌟 Unit 8: Photosynthesis & Bioenergetics
• Chlorophyll & light harvesting
• Photosystems I & II
• Water oxidation & O2-evolving complex
• ET in thylakoids
• ATP synth via chemiosmosis
• NADPH gen & carbon fixation
• Photoprotection & quenching
• Artificial photosynthesis & solar fuels
• Comparative photosynthesis

🌟 Unit 9: Metals in Medicine
• Medicinal bioinorg intro
• Pt anticancer drugs
• Au arthritis treatment
• Ag antimicrobial
• MRI contrast agents (Gd)
• Radioisotopes in imaging & therapy
• Metalloenzyme inhibitors & chelation

🌟 Unit 10: Toxicology
• Metal toxicity & heavy metal mech
• Pb & nervous system, Hg poisoning
• Cd & As toxicity
• Detox & chelation
• Occupational & environmental exposure

🌟 Unit 11: Biomineralization
• Def & importance
• CaCO3: shells, corals
• CaPO4: bones, teeth
• Silica in diatoms & magnetite in bacteria
• Organic matrices & controlled mineralization
• Medical apps & biomineralization-inspired materials

🌟 Unit 12: Future Directions
• Metallomics & systems biology
• Biomimetic chem & nanotech
• Metals in neurobiology & brain
• Synthetic models & metal complexes in renewable energy
• Interdisciplinary biophysics & medicine
• Emerging spectroscopic & imaging
• Grand challenges

✨This app is inspired by the authors:
Adrian Wells, Elena Morozova, Hiroshi Tanaka, Marta Gonzales & Kamran Siddiqui

📲 Download from Play Store for full Bioinorganic Chemistry Edition!