This Augmented Reality App invites you to experience an interactive journey illustrating key characteristics of Rett Syndrome (RTT), including its genetic underpinnings, pathophysiology, clinical manifestations, complications, burdens, and associated negative outcomes. Through this sensory-immersive experience, a series of perceptual information and imagery will incorporate strategies for providing a timely and accurate diagnosis of RTT into clinical practice, and to evaluate the clinical profiles of emerging therapeutic options for RTT to enhance the educational experience.