Science and technology is a topic that encompasses science, technology, and the interactions between the two. Science is a systematic enterprise that builds and organizes knowledge in the form of explanations and predictions about nature and the universe. Technology is the collection of techniques, methods or processes used in the production of goods or services or the accomplishment of objectives, such as scientific investigation, or any other consumer demands.

Science may drive technological development, by generating demand for new instruments to address a scientific question, or by illustrating technical possibilities previously unconsidered. In turn, technology may drive scientific investigation, by creating a need for technological improvements that can only be produced through research, and by raising questions about the underlying principles that a new technology relies on.

For the majority of human history, technological improvements were achieved by chance, trial and error, or spontaneous inspiration. When the modern scientific enterprise matured in the Enlightenment, it primarily concerned itself with fundamental questions of nature. Research and development directed towards immediate technical application is a relatively recent occurrence, arising with the Industrial Revolution and becoming commonplace in the 20th century.