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Info e questionnairs include:

· Record whether the patient brush his/her teeth

· Self-monitoring the number of cigarettes smoked per day

· Self-monitoring combustion free nicotine delivery system (C-F NDS) use

· Self-monitoring the continuing of non-smoking

· Monitoring the presence of Adverse Events (A/E) and Serious Adverse Events (SA/E)

· Record whether the patient use dental floss

· Record whether the patient use mouthwash

· Record whether the patient changes something regarding your usually oral hygiene habit (i.e new toothbrush, new toothpaste, new mouthwash, etc..)

Additionally, the SMILE app has several futures:

· Practical Step-Counter, that will help you to monitoring your physical activity

· Gamification system, with the possibility to win, collect and change virtual coins (Smile Coin) with amazing prizes

· Reminder system, that serves to remember the date and the time of the next visit and all the restriction to follow

· Possibility, whatever you want or need, to easily get in touch with your doctor

The SMILE app is available just for Android users that are enrolled in “SMILE STUDY”, an 18-month duration clinical study supported by COEHAR.

SMILE is FREE for the entire duration of the study."