On 19 April 2006, Kafrelsheikh University was established by the Presidential Decree No (129). Historically, the nucleus of the faculties started with the establishment of the Higher Agricultural Institute in 1957 in Kafrelsheikh governorate, affiliated with the Ministery of Higher Education. In 1969, the institute was transferred to the Faculty of Agriculture, affiliated with Alexandria University. The faculty was annexed to Tanta University after its establishment in 1973. In 1977, the Faculty of Education was established, and the Faculty of Specific Education was established in 1988. In the beginning, Faculty of Specific Education was affiliated with the Ministry of Higher Education, then by the Ministerial decree No 1187, it became affiliated with Tanta University. In 1922, a branch of the Faculty of Engineering was established. In 1997, a branch of Faculty of Physical Education was established.

When the Republican decree was issued to transfer Kafrelsheikh branch to an independent university and the branches of the faculties became faculties