Early graying of hair is defined as the appearance of white or gray hair before the age of 20 in Caucasians, and before 30 years in the African American population, which can severely affect an individual's self-esteem, and the exact reason for this is still unknown, although it is associated with disorders. Premature aging, atopic dermatitis, and autoimmune diseases, therefore, patients who begin to have white hair should be evaluated at an early age, and hair dyes remain the main method for treating cosmetic concerns for the appearance of white hair after nutritional supplements.